Parkinson's Disease tissue culture models
According to current understanding the majority of neuronal dysfunction and loss in case of PD are directly or indirectly caused by mitochondrial impairment. JSW Life Sciences provides different cell culture models for Parkinson's Disease using various mitochondria specific toxins known to induce cell death.
The following cultures can be treated with agents (e.g. MPP+) that induce lesions mimicking Parkinsonīs Disease:
Cultures are analysed for cell survival, apoptotic and necrotic phenotypes and mitochondria specific markers (see Analyses of culture models).
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